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When -synuclein reaches synaptic terminals, it causes templated misfolding of native neuronal -synuclein, allowing it to propagate trans-synaptically to linked neurons, similar to prion propagation

Refractory SLE patients respond to the proteasome inhibitor bortezomib

2.2 Animals Thirty-two male BALB/c mice, aged 68 weeks and weighing 1822 g, were provided by Jinan Pengyue Experimental Animal Breeding Co., Ltd

Accumulation of mitochondrial DNA deletions within dopaminergic neurons triggers neuroprotective mechanisms

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